The Department of Neurology, Creighton University Medical Center, is currently recruiting for:
RE: IRB # 98-11732
Parkinson’s Research: the Organized Genetics Initiative (PROGENI)
This study is a genetic study for siblings with Parkinson’s disease.
RE: IRB #06-14300
A Randomized, Double-blind, Active (Pramipexole 0.5 mg tid) and Placebo Controlled, Efficacy Study of Pramipexole, given 0.5 mg and 0.75 mg bid over a 12-Week Treatment Phase in Early Parkinson’s Disease Patients. (PramiBID)
This study is for recently diagnosed subjects with Parkinson’s disease comparing Pramipexole in various doses or placebo taken twice daily or three times daily to determine if it is effective given only twice daily.
RE: IRB # 07-14637
A Multicenter, Randomized, Double-blind, Placebo-Controlled, 5-Arm, Parallel Group Trial to Assess Rotigotine Transdermal System Dose Response in Subjects with Advanced-Stage Parkinson’s Disease
This is a study of various doses of the Rotigotine patch in subjects with Parkinson’s disease who experience 2.5 hours /day in the “off” state.
Closed for enrollment:
RE: IRB #05-13857
A Multi-center, Double-Blind, Randomized Start, Placebo-Controlled, Parallel-Group Study to Assess Rasagiline as a Disease Modifying Therapy in Early Parkinson’s Disease Subjects, Protocol: TVP-1012/500 (ADAGIO)
This study is comparing different doses of rasagiline versus placebo to determine if this drug slows down the progression of Parkinson’s disease.
RE: IRB # 05-13927
An Open-Label, Multicenter, Study of the Continued Safety of Istradefylline in Subjects With Parkinson’s Disease Who Have Recently Completed One Year of Treatment With Istradefylline
This study is to determine the long-term effectiveness and safety of this drug in subjects with Parkinson’s disease who experience wearing off of the effectiveness of their Levodopa.
RE: IRB # 06-14182
A Longitudinal Observational Follow-up of the PRECEPT study Cohort “POSTCEPT”
This study is following the long term progression of Parkinson’s disease in study subjects who previously participated in the PRECEPT study.
RE: IRB #06-14198
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Group
Study of the Efficacy, Safety, and Tolerability of E2007 in Levodopa Treated Parkinson’s Disease Patients with Motor Fluctuations (E2007-A001-302)
This study is testing the effectiveness and safety of the study drug E2007 in subjects with Parkinson’s disease who experience wearing off of their Levodopa.
